Hurry Up and Wait

You would think that as much waiting as we’ve had to do during the IVF process, we’d get better at it; but I guess practice doesn’t always make perfect.  We received a call this morning from the embryologist to update us on the development and growth of our embryos, so we wanted to pass it along.  Before we do that, we want to clear up all the numbers we’ve thrown around lately.

Number of eggs retrieved on Monday = 41

Number of mature eggs fertilized using ICSI (sperm injected into the egg) = 26

Number of embryos on Day 1 after fertilization = 21 (5 of the eggs didn’t successfully fertilize)

Number of embryos on Day 2 after fertilization = 21 (11 rated A- to B+, 10 rated B to B-)

That’s where we were as of Wednesday morning when the embryologist called us.  We had gone from 41 eggs to 21 embryos.  We didn’t get an update on Days 3 and 4.  On Day 3, the embryo cells continue to divide.  On Day 4, differentiation occurs.  During differentiation, some of the cells form a border around the edge of the embryo; these cells become the placenta.  Another group of cells clump up in the middle and will eventually become the baby.  You can clearly see these two groups of cells in the embryo that we transferred during Round 1.

 

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Transferred Embryo from Round 1

 

From what we’ve read and been told, a high rate of embryo arrest occurs on Day 4 during this differentiation stage.  We’ve heard it referred to as the “die off day.” So naturally, we expected our number to drop from 21.

This morning (Day 5), Breanne’s phone rang at 9:45, and we flew to it with me yelling, “Let me answer! Let me answer!”  The embryologist informed me that we had 6 embryos – 3 that looked really good and 3 that looked pretty good.  However, they weren’t quite ready to be frozen.  It sounded like great news to me, but when I told Breanne, I could see the worry in her eyes.  Like last time, it looks like we have some slow growers.  And last time, our embryos didn’t make it.  She made the connection pretty quickly and just sat in bed staring across the room.  I let her stare for a little while then asked, “Well, what are you feeling?”  She responded, “Chocolate.”  That’s not exactly what I meant, but it summed it all up.  I went and bought my wife lots of chocolate.  So much, in fact, that the lady at Livingston Sweet Shoppe asked me if we were having a party.  I said yes to avoid looking like too much of a fat kid.

The embryologist told me he would check the embryos again this evening, and if they were ready to be frozen, he would call.  If not, he would check again Sunday morning and call us.  Let me just stop right here and say that waiting on a phone call that may not even come is miserable.  As the eternal optimist in the relationship, I hung up with the embryologist this morning feeling really upbeat.  But as the day went on, my excitement turned to nervous anticipation.  Breanne’s sister called around 6:15 this evening, and I jumped.  I could feel my heart in my throat.  Her phone hasn’t rung since.

It’s 8:30 now, and at this point we aren’t expecting a phone call until tomorrow.  So, it looks like tonight will be another night of Tylenol PM and Netflix until we can’t hold our eyes open anymore.